Exam Code: A00-282
Exam Name: Clinical Trials Programming Using SAS 9.4
Certification Provider: SASInstitute
Corresponding Certification: SAS Clinical Trials Programming
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SASInstitute A00-282 Exam Syllabus Topics:

SectionObjectives
Topic 1: SAS Programming for Clinical Trials- Data Management
  • 1. Data cleaning and transformation
    • 2. Dataset merging and manipulation
      - Reporting and Analysis
      • 1. Statistical reporting with SAS procedures
        • 2. Listings, tables, and figures generation
          Topic 2: Regulatory and Clinical Research Concepts- Clinical trial workflow
          • 1. Regulatory submission basics
            • 2. Study design fundamentals
              Topic 3: Clinical Trials Data Standards- CDISC Standards
              • 1. SDTM structure and implementation
                • 2. ADaM datasets and analysis-ready data

                  SASInstitute Clinical Trials Programming Using SAS 9.4 Sample Questions:

                  1. Review the following procedure format:
                  PROC TTEST date=date;
                  class group-variable;
                  var variable;
                  run;
                  What is the required type of data for the variable in this procedure?

                  A) Categorical
                  B) Continuous
                  C) Character
                  D) Treatment


                  2. Which two features are captured by the events general observation class of SDTM? (Choose two.)

                  A) Investigational or therapeutic treatments
                  B) Planned protocol milestones
                  C) Planned evaluations
                  D) Subject characteristics


                  3. By default, the PROC FREQ in the code below produces an output object named CrossTabFreqs and the PROC MEANS produces an output object named Summary.
                  <insert code here>
                  proc freq data = Work.AE;
                  table USUBJID*AEPTCD;
                  run;
                  proc means data = work.LB max;
                  class USUBJID;
                  var STUDYDY;
                  run;
                  Which code segment can be added prior to the PROC FREQ step to ensure that PROC MEANS produces its output object but PROC FREQ produces no output object?

                  A) ODS SELECT Summary;
                  B) ODS EXCLUDE CrossTabFreqs;
                  C) ODS SELECT NONE:
                  D) ODS EXCLUDE ALL;


                  4. Which two SDTM domains store information for the experimental design of the trial?
                  (Choose two.)

                  A) TV
                  B) TE
                  C) TA
                  D) TD


                  5. A Statistical Analysis Plan defines study day as the number of days between the visit date and the date of randomization plus one day.
                  The following SAS program is submitted using a macro from the project's library:

                  How is the STUDYDAY macro defined?

                  A) %MACRO studyday(visit=, rand=);
                  &visit. ?&rand. + 1
                  %MEND studyday;
                  B) %MACRO studyday(rand=, visit=);
                  &vdt. ?&rdt. + 1
                  %MEND studyday;
                  C) %MACRO studyday(rand, visit);
                  &visit. ?&rand. + 1
                  %MEND studyday;
                  D) %MACRO studyday(rand, visit);
                  &vdt. ?&rdt. + 1
                  %MEND studyday;


                  Solutions:

                  Question # 1
                  Answer: B
                  Question # 2
                  Answer: B,C
                  Question # 3
                  Answer: B
                  Question # 4
                  Answer: B,C
                  Question # 5
                  Answer: C

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